Neurofibroma

What is it?

A neurofibroma is usually a benign peripheral nerve sheath tumor. If symptoms are present, they usually include pain and/or radicular sensory changes due to the typical location along the dorsal sensory roots. Weakness is less common. Myelopathy may occur if the lesion is large. The majority of localized neurofibromas are solitary and sporadic and not associated with neurofibromatosis type. However, when multiple neurofibromas are present then the diagnosis of neurofibromatosis type 1 is almost assured. Neurofibromas are treated with surgery, but unlike schwannomas, neurofibromas are not encapsulated and infiltrate between the nerve fascicles, making resection difficult.

Symptoms

Neurofibroma symptoms vary depending on the tumor type, size and location. Some people who have neurofibromas may never have symptoms. But sometimes, neurofibromas can cause serious medical issues such as paralysis or blindness. Some children who have plexiform neurofibromas develop scoliosis caused by tumors pressing into their spines.

Diagnosis

Healthcare providers typically use a physical examination to diagnose neurofibromas. They might also use the imaging tests such as computed tomography (CT) scan, magnetic resonance imaging (MRI), and positron emission tomography (PET) scan.

Treatment

If neurofibroma is benign and isn’t causing problems, doctor may recommend regular check-ups to monitor for changes. Plastic surgery is recommended for removing benign tumors that are on the surface of the skin or just beneath the skin. If neurofibromas pressing on bones or organs doctor may recommend surgery to remove as many tumors or as much of a tumor as possible without damaging the organs and tissues.